Sunday brings the initial Wear-Tyne derby after 2024, but who will emerge victorious – Sunderland or Newcastle?
"Throughout the majority of last season, it was unthinkable Sunderland earning promotion and being competitive with Eddie Howe's Newcastle, let alone being above them in the table," commented football expert Chris Sutton.
"It is very different now, and the way they play convinces me they've got a real chance."
Sutton is making predictions for all 380 Premier League games this season, against AI, the public and a variety of guests.
For the upcoming matchday, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is vying for victory for the eLions – the Football Association's official esports team – at the gaming title European esports championship finals tournament, which is being held at Twickenham Stadium on Saturday.
You can watch Uefa's YouTube, Instagram Live and TikTok channels, as well as the official Twitch channel and YouTube and the national team's Twitch.
What are your thoughts with their scores? You can make your own guesses below.
The fan-favourite scoreline selected for each game is used in the scoreboards at the end of this page.
A correct result (selecting a win, draw or defeat) is worth ten points. An accurate scoreline earns 40 points.
Ray, who also plays his club side and the Premier League champions as well as England, is making his debut at the eEuros finals after getting through the preliminary stage.
A group of eight will play for their countries at the finals in a knockout format, playing for a six-figure prize fund and a highly sought-after spot in the FC Pro World Championship Play-Ins, with Denmark's Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray remarked. "I have a really good coach by my side and preparation has been going well.
"Representing your country is always an honour to play for your country. Naturally when you are younger, you fantasise about doing it as an real-life footballer, but when you go into this profession and there is an chance to represent England, wearing the Three Lions is something incredible.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"In my opinion he is the number one in the world so getting a win over him in a tournament like this just delivers a crazy boost of confidence."
Stamford Bridge, 15:00 GMT
The Blues were impressive against Arsenal at the end of November, when they secured a point after being reduced to 10 men, and I was thinking this is it, they could potentially be title contenders.
Since then, however, they were overpowered by Leeds, looked flat against Bournemouth and this week got turned over by Atalanta in the Champions League.
So head coach Enzo Maresca is in need of a win here to get back on track, but it won't be easy because the Toffees are such a potent team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing really well and Everton have got a bit of form at the moment.
Based on recent performances you would probably back Everton, while the most prudent prediction would likely be a draw, but I am not going to be sensible.
They have not given me any real reason to back them recently, but I just have a gut instinct Chelsea will win this match because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Anfield, 15:00 GMT
I am at this game and it will be intriguing to see what we get from the Reds.
I was delighted for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the stuff with Mohamed Salah this week.
Slot should not have to put up with that nonsense. I know Salah has been a icon for the club but essentially Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond formation and two up top.
Everyone is going to be talking about whether Salah is selected for this game, but the only way he is going to be brought back into the fold is if he apologises.
Slot's primary concern will be on winning this game, but it is a challenging encounter.
One might suggest it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to winning consistently, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I have whacked a couple of Brighton players in my FPL team, so they will probably lose now - but I do fancy get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Stadium of Light, 14:00 GMT
The Wearside club have had the benefit of a free week while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
With the exception of their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, particularly straight after they've played in the Champions League.
The pattern suggests that tendency to continue on Sunday, and their fatigue is likely to be a factor in how this game goes because of their rivals' high press.
Their match against Arsenal demonstrated how relentless Regis le Bris's side are. They bullied the Gunners, and it was amazing to watch.
Commentators talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been superb, but Noah Sadiki, who plays in midfield with him, has also been one of the signings of the season and deserves some attention too.
I am expecting this being the best game|most exciting fixture
A former professional poker player turned gambling analyst, specializing in casino game strategies and responsible gaming practices.